US Patent:
20090312238, Dec 17, 2009
Inventors:
Daphna Sagher - Boca Raton FL, US
David Brunell - West Palm Beach FL, US
Herbert Weissbach - Boynton Beach FL, US
Assignee:
Florida Atlantic University - Boca Raton FL
International Classification:
A61K 38/02
C12N 5/06
G01N 33/53
A61P 39/06
US Classification:
514 6, 435325, 435375, 435 71
Abstract:
The present invention relates to the use of MT as a reducing system for the Msr enzymes and other oxioreductase enzymes which form similar intermediates. Specifically, the invention provides for a reduction in the level of oxidative damage in cells through an increase in levels of MT by administration of suitable compounds, resulting in an increase in the activity of the Msr enzymes.