Search

Craig Robert Monell

from La Jolla, CA
Age ~59

Craig Monell Phones & Addresses

  • 5971 Avenida Chamnez, La Jolla, CA 92037 (858) 539-0940
  • 1394 Caminito Balada, La Jolla, CA 92037
  • Boise, ID
  • 429 Sierra Ave, Solana Beach, CA 92075
  • Cardiff by the Sea, CA
  • 1560 Bella Vista Dr, Encinitas, CA 92024 (760) 942-4678 (858) 350-8387
  • 1580 Bella Vista Dr, Encinitas, CA 92024
  • San Diego, CA
  • Baltimore, MD

Publications

Us Patents

Binary Signaling Assay Using A Split-Polymerase

View page
US Patent:
7659069, Feb 9, 2010
Filed:
Aug 31, 2007
Appl. No.:
11/897892
Inventors:
Alexander Belyaev - San Diego CA, US
Craig Robert Monell - La Jolla CA, US
Joseph A. Sorge - Wilson WY, US
Assignee:
Agilent Technologies, Inc. - Santa Clara CA
International Classification:
C12Q 1/68
US Classification:
435 6, 435 912
Abstract:
The present invention provides methods, kits and compositions for the detection of an analyte. In the methods of the invention, a complex is formed between two or more analyte specific probes (ASP) and an analyte. The analyte specific probes each have a portion of a polymerase which interact to form a functional polymerase complex upon binding of the ASP to the analyte. The functional polymerase complex then generates a detectable signal which is indicative of the presence and/or amount of the analyte in the sample.

Method And Apparatus For Hyperlinked Graphics Tool

View page
US Patent:
20040044743, Mar 4, 2004
Filed:
Sep 29, 2003
Appl. No.:
10/257713
Inventors:
Craig Monell - Encinitas CA, US
Benjamin Kraft - San Diego CA, US
Diane Haines - Redondo Beach CA, US
Meng Fu Shih - San Diego CA, US
International Classification:
G06F015/16
G06F017/30
G06F007/00
US Classification:
709/217000
Abstract:
A method and apparatus that allows information to automatically be obtained from a remote database through a user constructed interactive graphic user interface. A hyperlink is associated with an icon or image file. The hyperlink connects the icon to data stored within a database. The data represents information related to the picture represented on the icon. The icons are collected and distributed electronically for incorporation into pictures. The resulting picture allows one to access the database, which is updated with information related to the pictures represented on the icons.

Protein Kinase And Phosphatase Substrates And Multiplex Assays For Identifying Their Activities

View page
US Patent:
20060046277, Mar 2, 2006
Filed:
Sep 1, 2004
Appl. No.:
10/931251
Inventors:
Alexander Belyaev - San Diego CA, US
Angelo Kolokithas - La Mesa CA, US
Craig Monell - La Jolla CA, US
International Classification:
C12Q 1/48
C12N 9/12
US Classification:
435015000, 435194000
Abstract:
The present invention provides protein kinase and protein phosphatase substrates, methods of detecting protein kinases and protein phosphatases, and kits for detection of protein kinases and protein phosphatases. The substrates, methods, and kits use multiple substrates that can easily be differentiated from all other substrates, thus enabling rapid and easy detection of protein kinase or protein phosphatase activities. The invention also provides methods of directionally cloning nucleic acids.

Target Nucleic Acid Signal Detection

View page
US Patent:
20070122827, May 31, 2007
Filed:
Oct 11, 2006
Appl. No.:
11/546675
Inventors:
Joseph Sorge - Del Mar CA, US
Carsten-Peter Carstens - San Diego CA, US
Craig Monell - La Jolla CA, US
Alexander Belyaev - San Diego CA, US
International Classification:
C12Q 1/68
C12P 19/34
US Classification:
435006000, 435091200
Abstract:
Provided herein are methods, compositions and kits for detecting a target nucleic acid. A target nucleic acid can be produced, for example, by a cleavage reaction in an assay for detection of biological samples. In one aspect, a described method comprises the following steps: hybridizing the target nucleic acid having a 5′ end and a 3′ end to a probe to form a circular hybridization complex; forming a covalent circular target nucleic acid using the probe as a template for nucleic acid synthesis; and detecting the covalent circular target nucleic acid.

Binary Signal Detection Assays

View page
US Patent:
20080050743, Feb 28, 2008
Filed:
Jun 22, 2007
Appl. No.:
11/821286
Inventors:
Joseph Sorge - Wilson WY, US
Carsten-Peter Carstens - San Diego CA, US
Craig Monell - La Jolla CA, US
Alexander Belyaev - San Diego CA, US
Assignee:
Stratagene California - La Jolla CA
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
The present invention provides methods, kits and compositions for the detection of an analyte. The invention is particularly suited for the detection and quantification of analytes in solution. In the methods of the invention a complex is formed between two or more analyte specific probes (ASP) and an analyte. The reactive moieties of the probes interact upon the binding of the analyte specific probes to the analyte. The reactive moieties generate a nucleic acid cleavage product which is detected and indicative of the presence of the analyte.

Analyte Detection Assays

View page
US Patent:
20100075307, Mar 25, 2010
Filed:
Jul 14, 2008
Appl. No.:
12/375570
Inventors:
Alexander Belyaev - San Diego CA, US
Craig Monell - La Jolla CA, US
Joseph Sorge - Wilson WY, US
International Classification:
C12Q 1/68
US Classification:
435 6
Abstract:
The present invention provides methods, kits and compositions for the detection of an analyte. In the methods of the invention, a binding molecule coupled to a first polymerase is incubated with a modified polynucleotide template to form a copy of the modified polynucleotide template without any modified nucleotides. The unmodified copy is detected in a second amplification/primer extension reaction using a second polymerase that is unable to amplify the modified polynucleotide template. Detection of the unmodified copy is indicative of the presence and/or amount of the analyte in the sample. In place of the binding molecule coupled to a first polymerase, a pair of analyte-specific probes can also be used. The first analyte specific probe comprises a first binding moiety and a first portion of a first polymerase and the second analyte specific probe comprises a second binding moiety and a second portion of the first polymerase. When the binding moieties are bound to the analyte the first and second portions of the polymerase interact to form a functional polymerase complex that is used to form a copy of the modified polynucleotide template without any modified nucleotides.

E2A/Pbx1 Fusion Protein Specific Monoclonal Antibodies

View page
US Patent:
58586822, Jan 12, 1999
Filed:
Aug 2, 1996
Appl. No.:
8/691997
Inventors:
Stefan Gruenwald - Encinitas CA
Craig Monell - La Jolla CA
Assignee:
Pharmingen - San Diego CA
International Classification:
G01N 33567
G01N 3353
G01N 33543
C07K 1600
US Classification:
435 71
Abstract:
A monoclonal antibody which specifically binds with an E2A/pbx1 fusion epitope.
Craig Robert Monell from La Jolla, CA, age ~59 Get Report