US Patent:
20180231546, Aug 16, 2018
Inventors:
- Cincinnati OH, US
Sancai Xie - Liberty Township OH, US
Benjamin Thomas Circello - Maineville OH, US
Cheryl Sue Tansky - Forest Park OH, US
Malgorzata Klukowska - Mason OH, US
Thomas Glenn Huggins - Mason OH, US
Deepa Ashok Khambe - Cincinnati OH, US
Donald James White - Fairfield OH, US
International Classification:
G01N 33/566
C12Q 1/6897
G01N 33/579
Abstract:
Methods for detecting and quantifying toxins present in the oral cavity. The methods may include providing a biological sample, providing reporter cells expressing one or more Toll like receptors, exposing the cells to the biological sample, measuring the EC50 value of the lipopolysaccharide on activation of a Toll like receptor, quantification of the lipopolysaccharide in the biological sample.