Inventors:
Russell Barnes - Columbus OH, US
Busolo Wabuyele - Columbus OH, US
International Classification:
A61B006/00
Abstract:
The invention discloses apparatus and methods that combine fluorescence spectra, Raman spectra, and diffuse reflectance, with image analysis in a single instrument package along with algorithms and data processing software. The data processing software involves spectral analysis, image analysis, data compression, data fusion, and classification processes. A spectral database with optical tissue characteristics is developed from a pathology laboratory and/or from in vivo measurements to provide the information required to differentiate normal and abnormal tissue.